In some studies, E171 was given to animals in drinking water without the stabilizers that keep E171 suspended in the liquid. Without stabilizers, E171 can settle and prevent the ingredient from combining with surrounding ingredients.

Panzhihua Dongfang Titanium Industry Co., Ltd. Dongfang, a well-known brand of titanium dioxide, a famous brand in Sichuan, a high-tech enterprise, a large supplier of titanium dioxide and titanium sponge, and one of the largest/leading titanium raw material production bases in China.